Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM254919(US9499542, 2 | US9675594, 2)
BDBM254919(US9499542, 2 | US9675594, 2)
BDBM254919(US9499542, 2 | US9675594, 2)
IC50: 170nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
BDBM254919(US9499542, 2 | US9675594, 2)
BDBM254919(US9499542, 2 | US9675594, 2)
IC50: 170nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
BDBM254919(US9499542, 2 | US9675594, 2)
IC50: 195nMpH: 8.5 T: 2°CAssay Description:LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...More data for this Ligand-Target Pair
BDBM254919(US9499542, 2 | US9675594, 2)
BDBM254919(US9499542, 2 | US9675594, 2)
EC50: 170nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...More data for this Ligand-Target Pair