Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50132989
(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90nM
Assay Description:
In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50132989
(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.10nM
Assay Description:
In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50132989
(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50132989
(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 78nM
Assay Description:
In vitro inhibitory activity against Mitogen-activated protein kinase p38
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI