Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 25 hits in this display
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 44nMAssay Description:Inhibition of ALK5 in human HaCaT cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 54nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in insect Sf9 cells using casein as substrate by radiometric kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 54.4nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 54.4nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 77nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 590nMAssay Description:Inhibition of recombinant human p38-alpha expressed in Escherichia coli using ATF2 as substrate by radioisotope-based assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 594nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 594nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 594nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 594nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radiometric kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
IC50: 668nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by proprietary radioisotopic protein kinase assayMore data for this Ligand-Target Pair
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
BDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)