Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50:  199nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed