Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50382325(CHEMBL2024693)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTGF-beta receptor type-1(Mus musculus)
Pfizer

Curated by ChEMBL

LigandBDBM50382325(CHEMBL2024693)Copy SMILESCopy InChI

Affinity DataIC50:  46nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI