Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandBDBM32483(piperazine amide, 6j)Copy SMILESCopy InChI

Affinity DataIC50:  1.80E+3nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute

LigandBDBM32483(piperazine amide, 6j)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+3nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI