Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053465
(1-(6-Methyl-pyridin-2-yl)-[1,2,4]triazinan-3-one |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.50E+3nM
Assay Description:
Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053465
(1-(6-Methyl-pyridin-2-yl)-[1,2,4]triazinan-3-one |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90E+3nM
Assay Description:
In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI