Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303828((S)-1-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataKi:  2nMAssay Description:Displacement of GS-red from human glucocorticoid receptor by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303828((S)-1-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataIC50: >4.00E+3nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303828((S)-1-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50:  31nMAssay Description:Transrepression activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of IL-1-beta-induced NF-kappaB dependent E-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303828((S)-1-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50:  25nMAssay Description:Transrepression activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of PMA-induced AP1 activity after 6 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303828((S)-1-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50:  920nMAssay Description:Transactivation of GAL-4 tagged glucocorticoid receptor ligand binding domain expressed in human HeLa cells assessed as NP1 activation by luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed