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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Acyl-CoA desaturase 1
(Mus musculus)
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50304944
(CHEMBL595474 | N-(2-hydroxy-2-phenylethyl)-6-(4-(2...)
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Affinity Data
IC50: 7nM
Assay Description:
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50304944
(CHEMBL595474 | N-(2-hydroxy-2-phenylethyl)-6-(4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fraction
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50304944
(CHEMBL595474 | N-(2-hydroxy-2-phenylethyl)-6-(4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of Scd1 in human HEK-293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acyl-CoA desaturase 1
(Mus musculus)
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50304944
(CHEMBL595474 | N-(2-hydroxy-2-phenylethyl)-6-(4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50304944
(CHEMBL595474 | N-(2-hydroxy-2-phenylethyl)-6-(4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of human Scd1 expressed in HEK-293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 h...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI