Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223993(8,8-dimethyl-3-[(3-methyl-thiophen-2-ylmethyl)-phe...)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223993(8,8-dimethyl-3-[(3-methyl-thiophen-2-ylmethyl)-phe...)
Affinity DataIC50:  6.40nMAssay Description:Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223993(8,8-dimethyl-3-[(3-methyl-thiophen-2-ylmethyl)-phe...)
Affinity DataIC50:  34.7nMAssay Description:Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed