Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 29 hits in this display   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  7nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  13nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  14nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  15nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  53nMAssay Description:Inhibition of cSRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  54nMAssay Description:Inhibition of TRKB by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  100nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  116nMAssay Description:Inhibition of c-RAF (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  180nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed