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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Aurora kinase A
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
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Affinity Data
Ki: 11nM
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
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Affinity Data
Ki: 15nM ΔG°: -45.4kJ/mole
pH: 7.5 T: 2°C
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Assay 1 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PubMed
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15.1nM
Assay Description:
Photometric_Method2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
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Affinity Data
Ki: 45nM
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM35664
(erk000628 | pyrimidylpyrrole, 11l)
Copy SMILES
Copy InChI
Affinity Data
Ki: 138nM
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI