Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50153335(CHEMBL3775834)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50153335(CHEMBL3775834)Copy SMILESCopy InChI

Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of full length human HALO-tagged KDM4C expressed in human U2OS cells assessed as level of H3K9Me3 demethylation incubated overnight by Hoe...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI