Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50439631(CHEMBL2419608)Copy SMILESCopy InChI

Affinity DataIC50:  65nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50439631(CHEMBL2419608)Copy SMILESCopy InChI

Affinity DataIC50:  68nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI