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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Arrien Pharmaceuticals
US Patent
Ligand
BDBM162020
(US9669028, 27 N-(1-(4-chlorobenzyl)piperidin-3-yl)...)
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Affinity Data
IC50: >500nM
Assay Description:
Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Arrien Pharmaceuticals
US Patent
Ligand
BDBM162020
(US9669028, 27 N-(1-(4-chlorobenzyl)piperidin-3-yl)...)
Copy SMILES
Affinity Data
IC50: >500nM
pH: 7.5
Assay Description:
The 2×DYRK1A/Ser/Thr 18 mixture was prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]
(Homo sapiens (Human))
Arrien Pharmaceuticals
US Patent
Ligand
BDBM162020
(US9669028, 27 N-(1-(4-chlorobenzyl)piperidin-3-yl)...)
Copy SMILES
Affinity Data
IC50: >500nM
Assay Description:
Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI