Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM77946(US10245267, Example 384 | US10709712, Example 384 ...)
IC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair