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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by
ChEMBL
Ligand
BDBM50345555
(3-(2-(2-methylthiazol-4-yl)ethynyl)-5-nitrofluorob...)
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Affinity Data
Ki: 0.300nM
Assay Description:
Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by
ChEMBL
Ligand
BDBM50345555
(3-(2-(2-methylthiazol-4-yl)ethynyl)-5-nitrofluorob...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.610nM
Assay Description:
Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI