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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Aldehyde dehydrogenase, dimeric NADP-preferring
(Homo sapiens (Human))
Indiana University Research And Technology
US Patent
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
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Affinity Data
IC50: 700nM
pH: 7.5
Assay Description:
IC50 values were determined for CB29 and its analogs using propionaldehyde as the substrate for ALDH1A1 and ALDH2 or benzaldehyde as the substrate fo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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US Patent
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Target
Aldehyde dehydrogenase, dimeric NADP-preferring
(Homo sapiens (Human))
Indiana University Research And Technology
US Patent
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
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Copy InChI
Affinity Data
IC50: 700nM
Assay Description:
Inhibition of human ALDH3A1-mediated benzaldehyde oxidation preincubated for 1 min followed by substrate addition by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Tumor necrosis factor
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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In Depth
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PCBioAssay
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Target
Nucleotide-binding oligomerization domain-containing protein 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nucleotide-binding oligomerization domain-containing protein 1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nucleotide-binding oligomerization domain-containing protein 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Nucleotide-binding oligomerization domain-containing protein 1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM62312
(2-methyl-1-(4-methylphenyl)sulfonyl-benzimidazole ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI