Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 15 hits in this display
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 5.30nM ΔG°: -43.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 8.60nM ΔG°: -42.8kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 300nM ΔG°: -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 3.70E+3nM ΔG°: -28.8kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 2.90E+4nM ΔG°: -24.1kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 6.70E+4nM ΔG°: -22.1kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 6.70E+4nMAssay Description:Displacement of [3H]-Epibatidine from rat alpha7 nACHR expressed in HEK293 cell membranes membranes by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 8.60E+4nM ΔG°: -21.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
Ki: 9.20E+4nM ΔG°: -21.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
IC50: 270nMAssay Description:IC50(10′): The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β...More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
IC50: >1.00E+4nMAssay Description:IC50(10′): The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β...More data for this Ligand-Target Pair
BDBM50428086(CHEMBL2323572 | US9303017, (S)-21, YL-1-235)
IC50: 1.10E+4nMAssay Description:IC50(10′): The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β...More data for this Ligand-Target Pair