Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Aptuit

Curated by ChEMBL

LigandBDBM50192308(CHEMBL3983121)Copy SMILESCopy InChI

Affinity DataKi:  0.417nMAssay Description:Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetD(2) dopamine receptor(Homo sapiens (Human))
Aptuit

Curated by ChEMBL

LigandBDBM50192308(CHEMBL3983121)Copy SMILESCopy InChI

Affinity DataKi:  66nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor expressed in CHO-K1 cell membranes coexpressing Galpha16 after 120 mins by liquid scin...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aptuit

Curated by ChEMBL

LigandBDBM50192308(CHEMBL3983121)Copy SMILESCopy InChI

Affinity DataIC50: >100nMAssay Description:Inhibition of human ERG transfected in HEK293 cells assessed as reduction in tail current by patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI