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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataKi:  10nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataKi:  10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MEK1 by cRaf/mek/Erk cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed