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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM26564
((3R,4R)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
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Affinity Data
Ki: 53nM
Assay Description:
The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM26564
((3R,4R)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
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Affinity Data
Ki: 1.12E+3nM
Assay Description:
The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM26564
((3R,4R)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
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Affinity Data
Ki: 3.31E+3nM
Assay Description:
The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM26564
((3R,4R)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
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Affinity Data
Ki: >3.33E+3nM ΔG°: >-31.3kJ/mole
pH: 7.5 T: 2°C
Assay Description:
The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Sus scrofa (pig))
Bristol-Myers Squibb
Ligand
BDBM26564
((3R,4R)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
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Affinity Data
IC50: 1.60nM
pH: 7.5 T: 2°C
Assay Description:
The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI