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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50375664
(CHEMBL404939 | US9422231, IMDNQ1)
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Affinity Data
IC50: 50nM
Assay Description:
Inhibition of Tpl2 kinase
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50375664
(CHEMBL404939 | US9422231, IMDNQ1)
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Affinity Data
IC50: 380nM
Assay Description:
Inhibition of MEK1
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tubulin alpha chain
(Trypanosoma cruzi)
Howard University
US Patent
Ligand
BDBM50375664
(CHEMBL404939 | US9422231, IMDNQ1)
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Affinity Data
IC50: 6.00E+3nM
pH: 6.9 T: 2°C
Assay Description:
Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50375664
(CHEMBL404939 | US9422231, IMDNQ1)
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Affinity Data
IC50: 3.45E+4nM
Assay Description:
Inhibition of Raf1
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 3
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50375664
(CHEMBL404939 | US9422231, IMDNQ1)
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Affinity Data
IC50: 8.29E+4nM
Assay Description:
Inhibition of ERK1
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI