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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
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Target
Replicase polyprotein 1ab
(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
Ki: 310nM
Assay Description:
This is a review article. Please point to the original journal.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
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Target
Chymase
(Homo sapiens (Human))
Kyoto Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibitory activity against human serine protease chymase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
PDB
Patents
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In Depth
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Article
PubMed
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Target
Cysteine protease ATG4B
(Homo sapiens (Human))
University Of Antwerp
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 630nM
Assay Description:
Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PDB
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Article
PubMed
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Target
Cysteine protease ATG4B
(Homo sapiens (Human))
University Of Antwerp
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 3.30E+3nM
Assay Description:
Inhibition of ATG4B (unknown origin) using proLC3B as substrate by FRET-LC3 assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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PubMed
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Target
Chymotrypsinogen A
(Bos taurus (bovine))
Kyoto Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 1.70E+4nM
Assay Description:
Inhibitory activity against alpha-chymotrypsin(alpha-CT)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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CHEMBL
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PC sid
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Article
PubMed
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Target
Cathepsin G
(Homo sapiens (Human))
Kyoto Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 2.40E+4nM
Assay Description:
Inhibitory activity against human leukocyte cathepsin G
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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Article
PubMed
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Target
Chymotrypsin-like elastase family member 2A
(Sus scrofa)
Kyoto Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 1.30E+5nM
Assay Description:
Inhibitory activity against porcine pancreatic elastase (PPE)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Trypsin
(Sus scrofa)
Kyoto Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50085339
(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
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Affinity Data
IC50: 2.10E+5nM
Assay Description:
Inhibitory activity against porcine pancreatic trypsin (TRP)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI