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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University

LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataKi:  310nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  630nMAssay Description:Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using proLC3B as substrate by FRET-LC3 assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed