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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Multidrug resistance-associated protein 1
(Homo sapiens (Human))
Xenova
Curated by
ChEMBL
Ligand
BDBM50140828
(4-{4-[2-(4-Chloro-phenyl)-ethyl]-piperazin-1-yl}-6...)
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Affinity Data
IC50: 399nM
Assay Description:
Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell line
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
ATP-dependent translocase ABCB1
(Mus musculus)
Xenova
Curated by
ChEMBL
Ligand
BDBM50140828
(4-{4-[2-(4-Chloro-phenyl)-ethyl]-piperazin-1-yl}-6...)
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Copy InChI
Affinity Data
IC50: 9.20E+3nM
Assay Description:
Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell line
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI