Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50202135(CHEMBL245897 | N-(4-chloro-2-((1,3-dioxoisoindolin...)Copy SMILESCopy InChI

Affinity DataEC50:  1.50E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL

LigandBDBM50202135(CHEMBL245897 | N-(4-chloro-2-((1,3-dioxoisoindolin...)Copy SMILESCopy InChI

Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI