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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
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Affinity Data
Ki: 15nM
Assay Description:
Inhibition of phosphorylated-Kdr after 30 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of KDR by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Vascular endothelial growth factor receptor 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Inhibition of vascular endothelial growth factor receptor 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
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Copy InChI
Affinity Data
IC50: 240nM
Assay Description:
Inhibition of Proto-oncogene tyrosine-protein kinase Kit
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
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Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of c-Src tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
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Affinity Data
IC50: 7.30E+3nM
Assay Description:
Inhibition of Epidermal growth factor receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Protein kinase A
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Met proto-oncogene tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Insulin-like growth factor I receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50132151
(CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Cyclin-dependent kinase 1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI