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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
)
Found
1
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Merz Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50438304
(CHEMBL2408413)
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Affinity Data
IC50: 722nM
Assay Description:
Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...
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