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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Apoptosis regulator Bcl-2/Glutathione S-transferase P
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM185602
(US9156856, 12 | US9493431, 12)
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Affinity Data
Ki: 393nM ΔG°: -36.6kJ/mole
T: 2°C
Assay Description:
Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM185602
(US9156856, 12 | US9493431, 12)
Copy SMILES
Copy InChI
Affinity Data
Ki: 393nM ΔG°: -36.6kJ/mole
T: 2°C
Assay Description:
Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI