Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50315118(4-(3-(4-chlorophenyl)-5-(1-(tetrahydrofuran-3-yl)p...)Copy SMILESCopy InChI

Affinity DataIC50:  31nMAssay Description:Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50315118(4-(3-(4-chlorophenyl)-5-(1-(tetrahydrofuran-3-yl)p...)Copy SMILESCopy InChI

Affinity DataIC50:  7.41E+3nMAssay Description:Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI