Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50345933(9-Allylamino-3-(4-chloro-phenyl)-3H-pyrido[3',2':4...)Copy SMILESCopy InChI

Affinity DataKi:  1.10nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50345933(9-Allylamino-3-(4-chloro-phenyl)-3H-pyrido[3',2':4...)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50345933(9-Allylamino-3-(4-chloro-phenyl)-3H-pyrido[3',2':4...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI