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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50383657
(CHEMBL2029846)
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Affinity Data
IC50: 90nM
Assay Description:
Inhibition of 5-lipooxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50383657
(CHEMBL2029846)
Copy SMILES
Copy InChI
Affinity Data
IC50: 320nM
Assay Description:
Inhibition of 5-lipooxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI