Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetPresenilin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50:  73nMAssay Description:Inhibition of gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed