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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Coagulation factor VII/Tissue factor
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50294169
(5-chloro-1H-indole | CHEMBL555013)
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Affinity Data
Ki: 4.30E+6nM
Assay Description:
Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
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PubMed
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Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
Decode Biostructures
Curated by
ChEMBL
Ligand
BDBM50294169
(5-chloro-1H-indole | CHEMBL555013)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
MMDB
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PC sid
PDB
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In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
Decode Biostructures
Curated by
ChEMBL
Ligand
BDBM50294169
(5-chloro-1H-indole | CHEMBL555013)
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Copy InChI
Affinity Data
IC50: 1.51E+6nM
Assay Description:
Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Nuclear receptor subfamily 4 group A member 2
(Homo sapiens (Human))
Goethe University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50294169
(5-chloro-1H-indole | CHEMBL555013)
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Affinity Data
Kd: 1.50E+4nM
Assay Description:
Binding affinity towards Nurr1 ligand binding domain (unknown origin) measured by microscale thermophoresis (MST) method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
PubMed
Copy BDB DOI