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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
Aristotle University
Ligand
BDBM24520
((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
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Affinity Data
Ki: 1.09E+6nM ΔG°: -16.9kJ/mole
pH: 7.0 T: 2°C
Assay Description:
SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Prostaglandin G/H synthase 1
(Ovis aries (Sheep))
Alexander Technological Education Institute Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM24520
((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
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Affinity Data
IC50: 1.25E+5nM
Assay Description:
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Seed linoleate 13S-lipoxygenase-1
(Glycine max (soybean))
Alexander Technological Education Institute Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM24520
((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
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Affinity Data
IC50: 1.26E+5nM
Assay Description:
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI