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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E]
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM32526
(pyridine amide, 34)
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Affinity Data
IC50: 2nM
T: 2°C
Assay Description:
11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...
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