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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
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Affinity Data
Ki: 0.600nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2S receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
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Affinity Data
Ki: 0.600nM
Assay Description:
Antagonist activity at D3 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
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Affinity Data
Ki: 10nM
Assay Description:
Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
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Copy InChI
Affinity Data
Ki: 23nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
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Affinity Data
Ki: 46nM
Assay Description:
Displacement of [3H]prazosin from human adrenergic alpha1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 125nM
Assay Description:
Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325744
(CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 125nM
Assay Description:
Antagonist activity at human H4 receptor expressed in CHO cells co-expressing Galphai2 assessed as inhibition of imetit-induced GTPgamma[35S] binding...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI