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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
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Affinity Data
Ki: 5nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
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Copy InChI
Affinity Data
Ki: 13nM
Assay Description:
Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 211nM
Assay Description:
Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 310nM
Assay Description:
Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 186nM
Assay Description:
Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.88E+3nM
Assay Description:
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.15E+3nM
Assay Description:
Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50299798
(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 49nM
Assay Description:
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI