Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM15627
(2-({4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-1H-pyrr...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 510nM ΔG°: -36.5kJ/mole
pH: 7.5 T: 2°C
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Vertex Pharmaceuticals
Ligand
BDBM15627
(2-({4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-1H-pyrr...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >4.00E+3nM
Assay Description:
A coupled spectrophotometric assay was used in which ADP generated by JNK3 was converted to ATP by pyruvate kinase with the production of pyruvate fr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI