Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8609((3-Pyridylmethylene)indane 25b | 3-{[(1Z)-4-chloro...)
Affinity DataIC50:  31nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8609((3-Pyridylmethylene)indane 25b | 3-{[(1Z)-4-chloro...)
Affinity DataIC50:  230nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8609((3-Pyridylmethylene)indane 25b | 3-{[(1Z)-4-chloro...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8609((3-Pyridylmethylene)indane 25b | 3-{[(1Z)-4-chloro...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8609((3-Pyridylmethylene)indane 25b | 3-{[(1Z)-4-chloro...)
Affinity DataIC50:  657nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed