Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL

LigandBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL

LigandBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL

LigandBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI