Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL

LigandBDBM50038593(CHEMBL301130 | Potassium ;2-(1-Carboxymethyl-2-oxo...)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Tested for 50% inhibition of thromboxane synthase (TxS) in human platelets (in vitro)More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Ciba-Geigy

Curated by ChEMBL

LigandBDBM50038593(CHEMBL301130 | Potassium ;2-(1-Carboxymethyl-2-oxo...)Copy SMILESCopy InChI

Affinity DataIC50:  6nMAssay Description:Tested for 50% inhibition of Angiotensin converting enzyme(ACE) obtained from rabbit lung (in vitro)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI