Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta-HSD1 by SPA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD1 by SPA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed