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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50260967
(3-(2-chloro-4-(2-(trifluoromethyl)-1H-imidazol-1-y...)
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Affinity Data
IC50: 0.960nM
Assay Description:
Inhibition of mouse 11beta HSD1 by SPA assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50260967
(3-(2-chloro-4-(2-(trifluoromethyl)-1H-imidazol-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.980nM
Assay Description:
Inhibition of human 11beta HSD1 by SPA assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50260967
(3-(2-chloro-4-(2-(trifluoromethyl)-1H-imidazol-1-y...)
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Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of mouse 11beta HSD2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50260967
(3-(2-chloro-4-(2-(trifluoromethyl)-1H-imidazol-1-y...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.20E+3nM
Assay Description:
Agonist activity at human PXR
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI