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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Merck
Curated by
ChEMBL
Ligand
BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
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Affinity Data
IC50: 1.70nM
Assay Description:
Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
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Copy InChI
Affinity Data
IC50: 2.80nM
Assay Description:
Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse))
Merck
Curated by
ChEMBL
Ligand
BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
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Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of mouse 11beta-HSD2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of human 11beta-HSD2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.80E+3nM
Assay Description:
Agonist activity at PXR
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI