Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed