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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 3nM
Assay Description:
In vitro binding affinity for Sigma opioid receptor by displacement of [3H]-DTG
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Histamine H1 receptor
(RAT)
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 7nM
Assay Description:
Displacement of [3H]- pyrilamine from rat brain membrane Histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
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CHEMBL
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PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 30nM
Assay Description:
Displacement of [3H]-prazosin from rat cortex membrane 5-hydroxytryptamine 1A receptor
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Target Info
PDB
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KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Muscarinic acetylcholine receptor M1
(RAT)
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 500nM
Assay Description:
Compound was evaluated in vitro for its binding affinity towards Muscarinic acetylcholine receptor M1 by displacing [3H]- telenzepine from rat brain ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 3.00E+3nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from rat hippocampus membrane 5-hydroxytryptamine 2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]- raclopride from rat striatum Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
Université
Curated by
ChEMBL
Ligand
BDBM50111627
(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
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Affinity Data
Ki: 2.00E+4nM
Assay Description:
Displacement of [3H]-ketanserin from rat cortex 5-HT3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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