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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM222969
(US9315518, 2-16)
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Affinity Data
EC50: 215nM
Assay Description:
The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Guanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM222969
(US9315518, 2-16)
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Copy InChI
Affinity Data
EC50: 64.1nM
Assay Description:
The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI