Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM175439(US9688680, 39)
Affinity DataIC50:  5.5nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [V560G,D816V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM175439(US9688680, 39)
Affinity DataIC50:  55nMT: 2°CAssay Description:10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM175439(US9688680, 39)
Affinity DataIC50:  550nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent