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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Eukaryotic translation initiation factor 2-alpha kinase 3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50396531
(CHEMBL2171132)
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Affinity Data
IC50: 1.30nM
Assay Description:
Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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Article
PubMed
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Target
Eukaryotic translation initiation factor 2-alpha kinase 3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50396531
(CHEMBL2171132)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of thapsigargin-induced autophosphorylation of PERK in human A549 cells after 2 hrs by Western blotting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50396531
(CHEMBL2171132)
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Affinity Data
IC50: 978nM
Assay Description:
Inhibition of PKR assessed as EIF2AK2 phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50396531
(CHEMBL2171132)
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Affinity Data
IC50: 1.86E+3nM
Assay Description:
Inhibition of HRI assessed as EIF2AK1 phosphorylation
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI