Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396531(CHEMBL2171132)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396531(CHEMBL2171132)
Affinity DataIC50:  30nMAssay Description:Inhibition of thapsigargin-induced autophosphorylation of PERK in human A549 cells after 2 hrs by Western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396531(CHEMBL2171132)
Affinity DataIC50:  978nMAssay Description:Inhibition of PKR assessed as EIF2AK2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396531(CHEMBL2171132)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of HRI assessed as EIF2AK1 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed